Flu Symptoms Drove Boston Mayor to Hospital

When Boston Mayor Thomas Menino ended his vacation in Italy short this fall and checked into a Boston hospital complaining of a respiratory infection, it led doctors to find and treat a blood clot in his leg, a fracture in his back, an infection around the fracture and type 2 diabetes.

Cold and flu symptoms from respiratory infections can be a hassle, but sometimes that fever and cough can be good for just getting people to the doctor.

“That’s why every patient needs a careful evaluation because every once in a while, what the patient thinks is the flu or reports as the flu is not,” said Dr. William Schaffner, chairman of preventative medicine at Vanderbilt University in Tennessee. “I would say 99 percent of people who present to the emergency room and doctor’s office with symptoms of influenza – that is cough, fever and the like – are certainly going to have influenza.”

Click here to read about cold- and flu-fighters.

Menino, 69, arrived at Brigham and Women’s Hospital on Oct. 25, complaining of fatigue and a cough, and doctors described him as “extremely washed out” with some “malaise.” In addition to the respiratory infection, doctors found a blood clot that traveled from Menino’s leg to his lungs.

Respiratory illnesses, like the one that initially drove Menino to seek medical attention, can often range from mild to severe, Schaffner said.

“He was feeling poorly enough to end what was supposed to be a very pleasant vacation, and when he got here, he was very weak and very washed out,” Dr. Dale Adler, Menino’s doctor, said during a press conference in mid-November.

Doctors can usually tell whether flu-like symptoms are the result of a respiratory infection or something else soon after the patient is admitted. If not, they can perform a series of tests to find out.

Click here to read about flu fact and fiction.

(The flu can lead to other ailments, the most common of which is pneumonia, or an infection of the lungs, Schaffner said.

About 1.1 million pneumonia patients were hospitalized and discharged in 2009, according to the latest data from the Centers for Disease Control and Prevention. On average, they stayed in the hospital 5.2 days.)

Weeks later, Menino was still in the hospital. Although his illness and clot had been resolved, he was complaining of back pain, which doctors discovered was the result of a compression fracture and an infection around the fracture.

Finally, doctors discovered that Menino had underlying type 2 diabetes, which may have contributed to the infection, Menino’s doctor said during a press conference on Monday.

It’s not clear how Menino’s initial flu-like symptoms tied into his other ailments, but doctors said they are positive about his prognosis. The mayor relocated to a rehabilitation center on Monday.

“It is a run of bad luck,” Morris said of Menino. “He will rebound from this.”

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Play Your Wii U Anywhere — Even on a Train

Wii U on a Train

No need for a TV set. If you plug the Wii U in, you can interact entirely with the GamePad. This is on a Japanese Shinkansen, a high-speed train.

Click here to view this gallery.

[More from Mashable: Nintendo Unveils Wii Mini for the Canucks]

Nintendo’s new Wii U console may have one real advantage over the competition: portability. Since you don’t need a television to play a good portion of the Wii U titles, gaming on the road is as easy as locating a power outlet.

Rocket News 24 tested the console’s mobility by taking a Wii U on a Japanese bullet train, which has power outlets at every seat. Thanks to that — and a little iPhone tethering magic — their staff was able to play New Super Mario Brothers U and Call of Duty Black Ops 2 while riding comfortably.

[More from Mashable: Wii U Sells 400,000 Units in First Week]

Check out Rocket News 24 to see more pictures and a full recount of their experience.

This story originally published on Mashable here.

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Rugby-England add flyhalf Burns to squad for All Blacks’ test

LONDON, Nov 27 (Reuters) – England called up uncapped Gloucester flyhalf Freddie Burns on Tuesday to their squad for Saturday’s test against New Zealand in place of the injured Toby Flood.

Flood sustained ligament damage to a big toe during the 16-15 loss to South Africa at Twickenham last Saturday.

Owen Farrell, whose last start was in the first test in South Africa this year, is set to replace Flood in the starting XV against the world champions.

Lock Courtney Lawes, who missed England’s first three tests of the November series because of a knee injury, has also been included in the 23-man squad. Two other locks, Mouritz Botha and Tom Palmer, have been omitted.

After beating Fiji in their opening match, England have lost to Australia and the Springboks and now face a daunting match against the All Blacks who are unbeaten in 20 tests since the start of their victorious World Cup campaign last year.

“For those in Saturday’s squad the message is clear – last week we went toe to toe with the second best team in the world and felt we should have won,” England head coach Stuart Lancaster said in a statement.

“Now we have a chance to take on the number one side in front of a passionate Twickenham crowd, who have been fantastic throughout the Internationals, and it is a challenge we will meet head on.” (Reporting by John Mehaffey; Editing by Ken Ferris)

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New York, New Jersey put $71 billion price tag on Sandy

(Reuters) - New York state and New Jersey need at least $71.3 billion to recover from the devastation wrought by Superstorm Sandy and prevent similar damage from future storms, according to their latest estimates.

The total, which could grow, came as New York Governor Andrew Cuomo said on Monday the state will need $41.9 billion, including $32.8 billion to repair and restore damaged housing, parks and infrastructure and to cover lost revenue and other expenses. The figure also includes $9.1 billion to mitigate potential damage from future severe weather events, Cuomo said.

Neighboring New Jersey, which saw massive damage to its transit system and coastline, suffered at least $29.4 billion in overall losses, according to a preliminary analysis released by Governor Chris Christie's office Friday. The preliminary cost estimate includes federal aid New Jersey has received so far.

By some measures, Sandy was worse than Hurricanes Katrina and Rita, which tore into the U.S. Gulf Coast in 2005, Cuomo said.

Sandy destroyed 305,000 houses in New York state - a still provisional number that's likely to grow - compared to the 214,700 destroyed in Louisiana by Katrina and Rita.

Sandy also caused nearly 2.2 million power outages at its peak in the state, compared to 800,000 from Katrina and Rita in Louisiana, and impacted 265,300 businesses compared to 18,700, Cuomo said.

While Sandy may have damaged more homes and businesses, Katrina took a far greater toll on human lives, killing more than 1,800 people directly or indirectly. Sandy, by comparison, is believed to have killed at least 121 people.

"Hurricane Katrina got a lot of notoriety for the way government handled -- or mishandled, depending on your point of view -- the situation," Cuomo said at a press conference.

But considering the dense population of the area Sandy impacted and costs to the economy, housing, and businesses, the damage done "was much larger in Hurricane Sandy than in Hurricane Katrina, and that puts this entire conversation, I believe, in focus," Cuomo said.

Sandy made landfall in New Jersey on October 29. It blasted through the Northeastern U.S., devastating homes, forcing evacuations, crippling power systems and shutting down New York City's subway system for days.

TAKING SANDY COSTS TO CONGRESS

The total cost to the region is still not known as estimates of the damage, as well as future repair and prevention costs, continue to come in from states, cities and counties.

New York City Mayor Michael Bloomberg said on Monday he will ask Congress for $9.8 billion to pay for Sandy costs not covered by insurance or other federal funds.

In a letter to New York's congressional delegation, Bloomberg said public, private and indirect losses to the city from the devastating late-October storm stood at $19 billion.

Of that, private insurance is expected to cover $3.8 billion, with Federal Emergency Management Agency reimbursements to cover at least an additional $5.4 billion, Bloomberg said in a statement.

The city still will need the additional $9.8 billion to help pay for costs that FEMA does not cover, like hazard mitigation, long-term housing, shoreline restoration and protection efforts, he said.

Whatever the final tally, officials are beginning to pressure Congress for federal assistance.

Cuomo met on Monday with the state's Congressional delegation and county officials. U.S. Senator Kirsten Gillibrand said in a statement that New York's Congressional delegation will push hard for additional federal funding.

"The federal government has a clear responsibility to commit all of the necessary resources to help us rebuild," she said.

Getting federal funds could be a tough fight, because of pressure on lawmakers to cut spending and raise taxes in order to shrink the federal deficit.

"This will be an effort that lasts not weeks, but many months, and we will not rest until the federal response meets New York's deep and extensive needs," said U.S. Senator Charles Schumer in a statement.

NUMBERS GAME

Cuomo's earlier estimates had pegged the total amount of damages for the region at $50 billion, with about $33 billion of that incurred in New York state.

In New York City, Bloomberg said on Monday that the city had about $4.8 billion of uninsured private losses, $3.8 billion of insured private losses, and $4.5 billion in losses to city agencies.

Reconstructing the city's damaged roads alone could cost nearly $800 million, Bloomberg said. New York City, a financial and tourism center, also lost about $5.7 billion in gross city product, he said.

Included in Cuomo's nearly $9.1 billion of mitigation costs are what he called "common sense" actions, like flood protection for the World Trade center site, roads, subway tunnels and sewage treatment plants, as well as power generators for the region's fuel supply system and backup power for health care facilities.

"We will see new projects," said Mysore Nagaraja, former president of the Metropolitan Transportation Authority's Capital Construction Co.

"In order to justify whatever money they finally end up getting, they have to come up with this list of projects that need to be done so that the future Sandy will not have the impact it had this time," he said.

Nagaraja is currently chairman of Spartan Solutions LLC, an infrastructure consulting firm.

(Reporting by Hilary Russ; Additional reporting by Daniel Trotta; Editing by Maureen Bavdek, Bill Trott and Phil Berlowitz)

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Beyonce to direct documentary about herself for HBO

LOS ANGELES (Reuters) – Pop superstar Beyonce is stepping behind the camera to direct a behind-the-scenes documentary about her personal and professional life, U.S. cable channel HBO said on Monday.

The currently untitled film will debut on February 16 and show the Grammy-winning singer’s life in the recording studio, readying for live performances and running her own TV and music production company.

“Everybody knows Beyonce’s music, but few know Beyonce the person,” HBO Programming President Michael Lombardo said in a statement. “Along with electrifying footage of Beyonce on stage, this unique special looks beyond the glamour to reveal a vibrant, vulnerable, unforgettable woman.”

The documentary will also feature moments in the “Crazy in Love” singer’s family life and first-person footage Beyonce captured on her laptop.

Beyonce, 31, who is married to hip hop artist and mogul Jay-Z, will headline the Super Bowl halftime show in New Orleans on February 3.

(Reporting By Eric Kelsey, editing by Jill Serjeant and Andrew Hay)

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HIV Vaccine Under Study May Last A Lifetime

A genetically-engineered HIV vaccine under study by Texas researchers works in a novel way.

It targets specific cells exactly where the virus enters the body, stimulating them to generate an immune response so the virus can’t take hold.

If the strategy bears out, the vaccine will be a single dose and last a lifetime, says Marie-Claire Gauduin, PhD, assistant scientist at Texas Biomedical Research Institute.

”Many other HIV vaccines try to block the infection when the virus is already in,” she says.  ”Here we try not to be infected to begin with,” Gauduin tells Take Part.

RELATED: Breakthrough: Early HIV Treatment Virtually Erases Risk of Passing Virus On

About 33 million people worldwide are living with  HIV/AIDS, according to estimates by the Joint United Nations Programme on HIV/AIDS.  Most do not know it. The new vaccine, if perfected, could be given to children at puberty to stem this toll, Gauduin says.

Most new cases of HIV infections worldwide are transmitted by sexual intercourse through outer layers of cells known as epithelial cells. These line the surfaces of structures throughout the body.

The target of the new vaccine is the mucosal layers of the epithelium in the genital and rectal areas, where the virus  typically enters.

“We are targeting the basal layer, the lower layer of epithelial stem cells,” she says. These stem cells divide and differentiate into specialized cell types.

The vaccine stays put in the epithelial stem cells, she says. Next, antigens that recognize the virus are produced.  ”These antigens stimulate your immune response to fight the virus,” she says.

“The virus will be recognized at the site of entry,” she says. “The virus won’t get to the blood stream is the hope.”

What makes it long lasting, she says, is the initial targeting of the stem cells. “Once the epithelial stem cell gets the message to stimulate your immune response, it will do so constantly,” she says, so the virus will be recognized long term.

Gauduin and her colleagues recently filed for a patent on the approach.

The vaccine, of course, is years from clinical practice, she says. “We have a lot of work to do,” she tells Take Part. Primate studies may start in early 2013. Human trials may begin as early as 2015.

Currently, other HIV vaccine approaches can’t deliver the antibody production for long periods of time. So the protection is weak and temporary, Gauduin says.

“It looks very interesting, certainly a great idea,” say Yegor Voronin, PhD, science officer for Global HIV Vaccine Enterprise, an alliance devoted to developing a preventive HIV vaccine.

RELATED: FDA Approves Truvada as First HIV Prevention Drug

The approach makes sense to scientists like him. “Epithelial cells don’t live very long,” he says. “They are continuously shed off. They are trying to affect the stem cells that produce epithelial cells. As the stem cells differentiate into epithelial cells, that is when they start producing the antigen.”

“It’s very early stages,” he says. “It’s an excellent idea. Whether it will work–who knows?”

Many other attempts have not panned out, he says.

One important as-yet unanswered question, he says, is whether the vaccine could cause some sort of health problem ”and you have the antigen being expressed continuously.” He asks: “How are you going to turn that off?”

Much safety testing, among other research, will be needed, he says.

As with other vaccines under development, he says a wait-and-see stance is best. “At this point, it’s just way too early to tell.”

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Kathleen Doheny is a Los Angeles journalist who writes about health. She doesn’t believe inmiracle cures, but continues to hope someone will discover a way for joggers to maintain their pace.

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132 online counterfeit sites seized in Cyber Monday blitz

WASHINGTON (Reuters) – U.S. and European authorities seized 132 domain names in a counterfeit goods crackdown linked to Cyber Monday, the online bargain day, the head of U.S. Immigration and Customs Enforcement said.

ICE agents seized 101 domain names in the United States and 31 were taken over by officers in Britain, Romania, Belgium, France and Denmark and by Europol, the European Police Office, ICE Director John Morton said.

The sites, many linked to organized crime, were selling fake goods that ranged from National Football League jerseys and Nike Inc shoes to Adobe Systems Inc software, he said.

“There is much money to be made out there duping consumers and that is what is going on,” Morton said on a conference call.

Investigations are ongoing and more sites will be seized in coming days.

In the United States, 41 rights owners’ merchandise was being sold on the seized sites, Morton said.

ICE said in a statement that one U.S. arrest had been made.

The crackdown marks the third year that ICE has targeted websites selling counterfeit goods on Cyber Monday, the online shopping spree. It is the first time the agency has carried out the operation with European police.

The Cyber Monday seizures raise the total number of U.S. sites taken over to 1,630 since ICE began its anti-counterfeit campaign in June 2010.

PayPal accounts identified with the sites and holding a total of more than $ 175,000 are being targeted for seizure, the ICE statement said.

Morton put the scale of online piracy in the billions of dollars. Much of the online counterfeiting is in China and other parts of Asia, and U.S. authorities are working with China on the problem, he said.

(Reporting by Ian Simpson; Editing by Dan Grebler)

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Dog days in Cuba: from shih tzus to schnauzers

HAVANA (AP) — The Cuban capital has played host to political summits and art festivals, ballet tributes and international baseball competitions. Now dog lovers are getting their chance to take center stage.

Hundreds of people from all over Cuba and several other countries came to a scruffy field near Revolution Plaza this past week to preen and fuss over the shih tzus, beagles, schnauzers and cocker spaniels that are the annual Fall Canine Expo’s star attractions. There were even about a dozen bichon habaneros, a mid-sized dog bred on the island since the 17th century.

As dog lovers talked shop, the merely curious strolled the field, checking out the more than 50 breeds on display while carefully dodging the prodigious output of so many dogs.

The four-day competition, which ended Sunday, included competitions in several breeding categories, and judges were flown in from Nicaragua, Colombia and Mexico.

“This is a small, poor country, but Cubans love dogs,” said Miguel Calvo, the president of Cuba’s dog federation, which organized the show. “We make a great effort to breed purebred animals of quality.”

Winners don’t receive any trophy or prize money, but that doesn’t mean the competition is any less fierce.

Anabel Perez, owner of a cocker spaniel named Lisamineli after the U.S. actress, spent more than half an hour coifing the dog’s hair in preparation for the competition, while the owner of a shih tzu named Tiguer meticulously brushed his coat nearby.

“I’m a hairdresser for humans,” explained Tiguer’s owner, Miguel Lopez. “So it’s easy for me. I like shih tzus because they are a lot of work to keep well groomed.”

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Workers killed in Bangladesh fire were making clothes for U.S. brands

The 100-plus workers who died in a fire late Saturday at a high-rise garment factory in Bangladesh were working overtime making clothes for major American retailers, including Wal-Mart, according to workers' rights groups.

Officials in Bangladesh said the flames at the Tazreen Fashions factory outside Dhaka spread rapidly on the ground floor, trapping those on the higher floors of the nine-story building. There were no exterior fire escapes, according to officials, and many died after jumping from upper floors to escape the flames.

As firemen continued to remove bodies Sunday, officials said at least 112 people had died but that the number of fatalities could go higher.

The Tazreen fire is the latest in a series of deadly blazes at garment factories in Bangladesh, where more than 700 workers, many making clothes for U.S. consumers, have died in factory fires in the past five years. As previously reported by ABC News, Bangladesh has some of the cheapest labor in the world and some of the most deplorable working conditions.

READ the original ABC News report.

"The industry and parent brands in the U.S. have been warned again and again about the extreme danger to workers in Bangladesh and they have not taken action," said Scott Nova, executive director of the Worker Rights Consortium, an American group working to improve conditions at factories abroad that make clothes for U.S. companies. Nova said the fire was the most deadly in the history of the Bangladesh apparel industry, and "one of the worst in any country."

WATCH the 'Nightline' report on deadly factories.

Workers' activists went into the burned-out remains today to document which major retailers were using the Tazreen factory.

They say they found labels for Faded Glory, a Wal-Mart private label, along with labels they said traced back to Sears and a clothing company owned by music impresario Sean "Diddy" Combs.

"There's no question that Wal-Mart and the other customers at this factory bear some blame for what happened in this factory," Nova said.

Nova also said that Wal-Mart "knew exactly what's going on at these facilities. They have staff on site in Bangladesh."

Wal-Mart actually warned of dangerous conditions at the Tazreen factory last year, in a letter posted online by the factory owner.

Wal-Mart told ABC News that the company has not yet been able to confirm that it was still making clothes at the factory.

In a statement, Wal-Mart told ABC News, "Our thoughts are with the families of the victims of this tragedy. ... [F]ire safety is a critically important area of Wal-Mart's factory audit program and we have been working across the apparel industry to improve fire safety education and training in Bangladesh.

"As part of this effort, we partnered with several independent organizations to develop and roll out fire safety training tools for factory management and workers. Continued engagement is critical to ensure that reliable, proactive measures are in place to reduce the chance of factory fires. "

Spokespeople for Combs and Sears did not immediately respond to requests for comment.

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Grammy-winning bassist injured in Swiss bus crash

GENEVA (AP) — Grammy-winning jazz bassist Marcus Miller and several members of his band were injured when their bus overturned Sunday on a busy highway in Switzerland, killing the driver, police said.

The German-registered private bus tipped over as it drove into a bend on the A2 highway in central Switzerland and came to a rest on its side, police in the canton (state) of Uri said. The bus was carrying 13 people — two drivers and 11 members of the Marcus Miller Band, including Miller.

Over his career, the bassist has worked with jazz greats such as Miles Davis, Dizzy Gillespie and Wayne Shorter, according to his website. He won two Grammys, his first coming in 1991 for Best Rhythm & Blues Song (“Power of Love”) along with Luther Vandross and Teddy Vann, and the second came in 2001 for Best Contemporary Jazz Album (“M2″).

The band was on its way from Monte Carlo to the Dutch town of Hengelo, the next stop on the American band’s tour, where it was due to perform Monday.

The driver who was at the wheel at the time of the accident sustained fatal injuries. Police spokesman Karl Egli said the 12 passengers were injured and taken to hospitals, but none had life-threatening injuries.

Miller was discharged from the hospital later Sunday, as were fellow band members Alex Han and Kris Bowers, but some other band and crew members were being kept in hospitals overnight, according to a post on Miller’s official Facebook page.

The cause of the accident was not immediately clear. Police believe no other vehicles were involved.

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